Articles from Wiley
Metal–Organic Framework Supported on Processable Polymer Matrix by In Situ Copolymerization for Enhanced Iron(III) Detection
The in situ copolymerization strategy was developed to integrate a mesoporous metal–organic framework (MOF) material with pre-designed active groups into the organic polymer matrix. The targeting MOF polymer composite is transparent, elastic, and processable with desired shape and thickness, which also shows an enhanced capability for FeIII ion detection due to the synergistic effect of composite with the newly formed bonding between MOF particle and polymer matrix. More information can be found in the Full Paper by S.-M. Fang and M. Du et al. (DOI: 10.1002/chem.201604210).
Chun-Sen Liu, Min Chen, Jia-Yue Tian, Lei Wang, Min Li, Shao-Ming Fang, Xi Wang, Li-Ming Zhou, Zhuo-Wei Wang, Miao Du
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201700132. Read article
Metal–organic framework (MOF) thin films and MOF membranes were prepared with a step-by-step spray method. Membrane performance was demonstrated by separation of a H2/CO2 mixture with HKUST-1 MOF membranes. Apart from controlling MOF film thickness, and thus the membrane permeance and selectivity, this approach enables a straightforward scale-up to large, industrially relevant membrane areas.
Silvana Hurrle, Sebastian Friebe, Jonas Wohlgemuth, Christof Wöll, Jürgen Caro, Lars Heinke
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201606056. Read article
Multichromophoric Perylenediimide–Silicon Phthalocyanine–C<sub>60</sub> System as an Artificial Photosynthetic Analogue
A multichromophoric perylenediimide–silicon phthalocyanine–C60 system has been synthetized. Successful occurrence of sequential energy transfer followed by electron transfer in a newly synthesized covalently linked triad composed of perylenediimide, silicon phthalocyanine and C60 as building blocks, in both polar and nonpolar solvents, has been demonstrated. The cover represents the beauty of the molecule as a mermaid where the C60 is the head, the body the phthalocyanine and the perylenediimide the tail. More information can be found in the Full Paper by F. D′Souza, A. Sastre-Santos et al. on page ▪▪ ff. (DOI: 10.1002/chem.201603741).
Luis Martín-Gomis, Francisco Peralta-Ruiz, Michael B. Thomas, Fernando Fernández-Lázaro, Francis D'Souza, Ángela Sastre-Santos
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201606033. Read article
Working in tandem: Enantioselective tandem Michael–aldol and oxidative Michael–aldol approaches have been realized for the synthesis of tetrasubstituted cyclohexanes, enabling the installation of multiple stereogenic centers in a single operation. The architecturally complex cyclohexane products have been transformed to a number of useful molecules. The present strategy has also been applied to the enantioselective formal synthesis of ABT-341.
Nirmal K. Rana, Harshit Joshi, Rupesh K. Jha, Vinod K. Singh
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605999. Read article
A Cryptand Metal–Organic Framework as a Platform for the Selective Uptake and Detection of Group I Metal Cations
Detector MOF: (H3O)2[Zn4(ur)(Hfdc)2(fdc)4] (1, ur=urotropine, H2fdc=furan-2,5-dicarboxylic acid) incorporates cryptand-like cavities, which can be used to separate and detect Rb+ and Cs+ optically. This is the first example of the effective employment of a MOF material for optical detection of these cations.
Sergey A. Sapchenko, Pavel A. Demakov, Denis G. Samsonenko, Danil N. Dybtsev, Martin Schröder, Vladimir P. Fedin
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605895. Read article
Probing the Peroxycarbenium [3+2] Cycloaddition Reactions with 1,2-Disubstituted Ethylenes: Results and Insights
Mission impossible: The peroxycarbenium [3+2] cycloaddition reaction with 1,2-disubstituted ethylenes, an impossible challenge to date, was achieved for the first time. An oxygen or N-Boc group at the double bond was proven essential for the acquisition of intact cycloaddition products. Otherwise, the cycloaddition may “fail” because product rearranged completely even at low temperatures.
Ze-Jun Xu, Sergio Wittlin, Yikang Wu
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605871. Read article
Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates
Excess electron transfer (EET) can be modulated within DNA by introducing a dimethylaminopyrene (C-AP) base surrogate as an electron donor, 5-bromouracil (BrdU) as an electron acceptor, and by changing the electronic nature of the phenanthrenyl pair.
Pascal Roethlisberger, Veerabhadrarao Kaliginediand, Christian J. Leumann
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605846. Read article
Synthesis of a Double-Network Supramolecular Hydrogel by Having One Network Catalyse the Formation of the Second
Encore! A double-network hydrogel with tuneable mechanical strength is presented in which catalytic activity of a self-assembling hydrogelator is responsible for in situ formation of the second network. The kinetics of the in situ formation of the second network could be controlled by using a catalytic hydrogelator, which becomes active upon self-assembly.
Nishant Singh, Chandan Maity, Kai Zhang, César A. Angulo-Pachón, Jan H. van Esch, Rienk Eelkema, Beatriu Escuder
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605771. Read article
Bichromophoric Compounds with Orthogonally and Parallelly Arranged Chromophores Separated by Rigid Spacers
Novel bichromophores: A novel strategy to prepare bichromophores with fixed interchromophore distance and orientation provides ideal model compounds to study intramolecular excitation energy transfer (EET) between orthogonal or parallel arranged chromophores. Bichromophores with like (blue-blue) and unlike (blue-red) chromophores show fast and efficient EET regardless of the orthogonal or parallel geometry.
Dirk N. H. Meineke, Mariano L. Bossi, Haisen Ta, Vladimir N. Belov, Stefan W. Hell
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605587. Read article
“Ethics in Chemistry” is a vast field with many facets for which this Editorial provides some clarity. It points out the “hot topics” that chemists deal with in their professional activities and offers recommendations on particular modes of action: compliance to ethical guidelines of chemistry and active participation in the broader discourse on ethical and social implications of chemistry.
Jan Mehlich, Frank Moser, Brigitte Van Tiggelen, Luigi Campanella, Henning Hopf
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605259. Read article
<b>Highly Enantioselective Ferrocenyl Palladacycle-Acetate Catalysed Arylation of Aldimines and Ketimines with Arylboroxines</b>
A planar chiral ferrocenyl palladacycle acetate complex catalyzes the 1,2-addition of arylboroxines to N-sulfonyl aldimines and cyclic ketimines with high enantioselectivity. Spectroscopic studies suggest that 1) a monomeric species is the active catalyst, 2) the acetate ligand promotes the transmetallation, 3) the product release is rate-limiting for aldimines. With ketimines additional acetate is necessary for high enantioselectivity causing a switch of the preferred enantiomer.
Carmen Schrapel, Wolfgang Frey, Delphine Garnier, René Peters
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605244. Read article
Turn cells blue: 1,1′-Spirobiindane-7,7′-diol (SPINOL)-based chiral aldehydes, in combination with Zn2+, are highly enantioselective fluorescent sensors for structurally diverse chiral amino acids. In HeLa cells containing a free amino acid, the chirality-matched sensor–amino acid interaction leads to strong blue emission and chirality mismatch gives only weak fluorescence (see figure).
Chaoyuan Zeng, Xiaoling Zhang, Lin Pu
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201605028. Read article
Constructing Implantable SrTiO<sub>3</sub>:Yb,Ho Nanofibers for NIR-Triggered and Optically Monitored Chemotherapy
Rule with a rod: Implantable polyacrylic acid (PAA)-modified SrTiO3:Yb,Ho nanofibers were synthesized. Owing to electrostatic bonding between the PAA and DOX molecules (see figure), low pH and NIR (λ=808 nm) irradiation both induced accelerated DOX release and consequently enhanced the local cancer-cell-killing effect. The ratio of green-to-red emission from the nanofibers responded effectively to the DOX release progress and enabled dosage monitoring.
Yike Fu, Chao Fang, Zhaohui Ren, Gang Xu, Xiang Li, Gaorong Han
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604956. Read article
O2 on time: The oxidation of organic phenylselenides by H2O2 provides fast and efficient in situ oxidants. A combined NMR and computational investigation is presented on four model compounds, that is the alkyl aryl selenide PhSe(nBu), the bis(phenylselanyl)alkanes PhSeMeSePh and PhSeEtSePh, and the diaryl diselenide PhSeSePh. On mechanistic and energy basis, suggestions for the choice of the most suitable organoselenium catalyst are discussed.
Giovanni Ribaudo, Massimo Bellanda, Ileana Menegazzo, Lando P. Wolters, Marco Bortoli, Gerardo Ferrer-Sueta, Giuseppe Zagotto, Laura Orian
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604915. Read article
Made to measure: The treatment of nanostructured microporous heteropolysalts with a basic agent allows tailored mesoporosity in solid materials to be developed with control over both the mesoporous volume and pore size (see picture; POM=(NH4)3[PMo12O40]). The mesoporosity originates from alkaline degradation in the core of the nanocrystals that aggregate to form the particles, thus resulting in independent micro- and mesoporous structures.
Juan Alcañiz-Monge, Guido Trautwein, Bouchra El Bakkali, Santiago Reinoso
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604879. Read article
Three-Dimensional Fibrous Network of Na<sub>0.21</sub>MnO<sub>2</sub> for Aqueous Sodium-Ion Hybrid Supercapacitors
Get a load: Aqueous Na-ion hybrid supercapacitors (SCs) based on a three-dimensional network of NaMnO2 were developed. The cathode material was synthesized by electro-oxidation of potassium manganese hexacyanoferrate nanocubes and was used to develop high-potential, high-performance aqueous SCs with a cell potential of 2.7 V. Practical applicability of an SC based on NaMnO2 (cathode) and reduced graphene oxide (rGO, anode) was demonstrated by powering a 2.1 V red LED.
Natarajan Karikalan, Chelladurai Karuppiah, Shen-Ming Chen, Murugan Velmurugan, Periyasami Gnanaprakasam
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604878. Read article
Perylene Bisimide Cyclophanes with High Binding Affinity for Large Planar Polycyclic Aromatic Hydrocarbons: Host–Guest Complexation versus Self-Encapsulation of Side Arms
Guest binding versus self-encapsulation: Cyclophanes comprising core-disubstituted perylene bisimide (PBI) subunits efficiently bind planar aromatic hydrocarbons with binding constants up to >106 m−1 in chloroform. These newly designed cyclophanes also exhibit self-encapsulation of side groups leading to fluorescence quantum yields of up to unity by preventing PBI–PBI interaction.
Peter Spenst, Andreas Sieblist, Frank Würthner
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604875. Read article
Classic inhibitors, such as AUY922, exhibit poor binding affinity for Hsp90 in cell lysate, and they induce a stress response in cells, which includes the overproduction of multiple HSPs at protein expression levels. This cellular phenotype is different from that seen in the Hsp90α knockdown cells, in which the production of HSPs is slightly decreased. The large increase in Hsp70 produced when cells are treated with classical inhibitors is consistent with other drugs that induce cellular stress. A combined CRISPR phenotype and pulldown data shows that classical Hsp90 inhibitors likely suppress cell growth via multiple mechanisms, which may or may not include the inhibition of Hsp90.
Yao Wang, Yen Chin Koay, Shelli R. McAlpine
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604807. Read article
Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications
JAGG versus HAGG: Colloidal nanoparticles (NPs) containing near-infrared-fluorescent J-aggregates (JAGGs) of pyrrolopyrrole cyanines stabilized by amphiphilic block co-polymers were prepared in aqueous medium. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, ideal for long-term bioimaging (see figure). Analogues with extended conjugation form weakly fluorescent H-aggregates (HAGGs).
Cangjie Yang, Xiaochen Wang, Mingfeng Wang, Keming Xu, Chenjie Xu
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604741. Read article
How Do Phosphinates React with Unactivated Alkenes Under Organic Photocatalyzed Conditions? Substrate Scope and Mechanistic Insights
When visible light meets H-phosphinates: Efficient C−P bond-formation reactions of two H-phosphinates with unactivated alkenes was achieved by visible-light irradiation under metal-free conditions (see scheme). The scope and limitations of this approach were investigated, and a detailed mechanistic study was carried out.
Giovanni Fausti, Fabrice Morlet-Savary, Jacques Lalevée, Annie-Claude Gaumont, Sami Lakhdar
Chem. Eur. J., January 20, 2017, DOI: 10.1002/chem.201604683. Read article